Publications

  1. Qiu, T.;  Kathayat, R. S.; Cao, Y.; Beck, M. W.; Dickinson, B. C. Biochemistry 2017 Just Accepted DOI: 10.1021/acs.biochem.7b00835 "A Fluorescent Probe with Improved Water Solubility Permits the Analysis of Protein S-Depalmitoylation Activity in Live Cells"

  2. Beck, M. W.; Derrick, J.S.;  Suh, J.-M.; Kim, M.; Korshavn, K. J.; Kerr, R. A.; Cho, W. J.; Larsen, S. D.; Ruotolo, B. T.; Ramamoorthy, A.; Lim, M. H. ChemMedChem 2017 Early View. DOI: 10.1002/cmdc.201700456 "Minor Structural Variations of Small Molecules Tune Regulatory Activities toward Pathological Factors in Alzheimer's Disease

  3. Beck, M. W.; Kathayat, R. S.; Cham, C. M.; Chang, E. B.; Dickinson, B. C. Chem. Sci. 2017 Advance Article DOI: 10.1039/C7SC02805A. "Michael Addition-Based Probes for Ratiometric Fluorescence Imaging of Protein S-Depalmitoylases in Live Cells and Tissues"

  4. Beck, M. W.; Derrick, J. S.; Kerr, R. A.; Oh,  S. B.; Cho, W. J.; Lee, S. J. C.; Ji, Y.; Han, J.; Tehrani, Z. A.; Suh, N.; Kim, S.; Larsen, S. D.; Kim, K. S.; Lee, J.-Y.; Ruotolo, B. T.; Lim, M. H. Nature Commun. 2016, 7, 13115. "Structure-Mechanism-Based Engineering of Chemical Regulators Targeting Distinct Pathological Factors in Alzheimer’s Disease"

  5. Beck, M. W.; Oh, S. B.; Kerr, R. A.; Lee, H. J.; Kim, S. H.; S; Kim, S.; Jang, M.; Ruotolo, B. T.; Lee, J.-Y.; Lim, M. H. Chem. Sci. 2015, 6, 1879. "A Rationally Designed Small Molecule for Identifying an In Vivo Link of Metal-Amyloid-β Complexes to the Pathogenesis of Alzheimer's Disease"  

  6. Beck, M. W.; Pithadia, A. S.; DeToma, A. S.; Korshavn, K. J.; Lim, M. H. Chapter 10: "Ligand Design to Target and Modulate Metal-Protein Interactions in Neurodegenerative Diseases." In Ligand Design in Medicinal Inorganic Chemistry John Wiley & Sons: Chichester, England, 2014.

  7. Liu, Y.; Kochi, A.; Pithadia, A. S.; Lee, S.; Nam, Y.; Beck, M. W.; He, X.; Lee, D.; Lim, M. H. Inorg. Chem., 2013, 52, 8121. "Tuning Reactivity of Diphenylpropynone Derivatives with Metal-Associated Amyloid-β Species via Structural Modifications"

  8. Pithadia, A. S.; Kochi, A.; Soper, M. T.; Beck, M. W.; Liu, Y.; Lee, S.; DeToma, A. S.; Ruotolo, B. T.; Lim, M. H. Inorg. Chem. 2012, 51, 12959. "Reactivity of Diphenylpropynone Derivatives Toward Metal-Associated Amyloid-β Species"